Cancer Zodiac Sign and Astrological Symbol The Cancer zodiac sign is represented by the crab, symbolizing their ability to protect themselves with their hard outer shell while remaining soft and vulnerable on the inside. Cancer is the fourth sign of the zodiac and is ruled by the moon, which influences their emotional and intuitive nature. Those born under this sign, typically between June 21 and July 22, are known for their nurturing and compassionate qualities. Cancer: Date